{"id":174,"date":"2022-09-30T19:48:02","date_gmt":"2022-09-30T19:48:02","guid":{"rendered":"https:\/\/stealthsyndromesstudy.com\/?p=174"},"modified":"2023-06-21T20:51:31","modified_gmt":"2023-06-21T20:51:31","slug":"of-mice-and-humen-ultimate-accuracy-in-clinical-trials-must-be-performed-on-people","status":"publish","type":"post","link":"https:\/\/www.stealthsyndromesstudy.com\/?p=174","title":{"rendered":"Mice Are Not People: Why The Most Important Studies Done With Them Ultimately Fail In Humans"},"content":{"rendered":"

Pharmaceutical studies are among the most demanding scientific investigations because the results can be a matter of life or death. Astonishingly, 92% of drugs deemed safe and effective in animals, fail when tested in humans<\/a>.<\/p>\n

The murine model<\/a> — mostly mice and sometimes rats — is invaluable in the preliminary stages<\/a> of investigating pharmaceuticals and toxic chemicals. However, when the ultimate decision needs to be made — such as approving a drug for use — only human experimental subjects will suffice. In many other types of studies, human tests are vital, but cannot be performed for ethical reasons.<\/p>\n

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But when ethical and practical concerns can be accommodated, humans are the gold standard. And when that gold standard is used, it surpasses murine test results about 90% of the time.<\/p>\n

Here is some background on how rats became star test subjects: Rats are Not Little People — But Science Assumes That They Are<\/a>.<\/p>\n

More Referencess<\/strong><\/p>\n