The Study

Playing Whack-A-Mole With Plastics And Your Health

This is a true tale for modern consumers, based upon results from a scientific paper from the Center for Research on Environmental Chemicals In Humans. To comment, please email CRECH Center Chairman and study main author Lewis Perdue. In science, as well as in classic mysteries, that which is missing often provides a pivotal clue […]

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Published trial results indicate that all dietary interventions so far are not replicable. New protocols suggested to assure reproducible, useful results

The text as published at medRxiv is at this link: Investigating hsCRP as a clinical inflammation marker for human Bisphenol A food contamination offers protocol suggestions for conducting replicable, causal dietary intervention studies Investigating hsCRP as a clinical inflammation marker for human Bisphenol A food contamination offers protocol suggestions for conducting replicable, causal dietary intervention […]

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Moving toward the trial: Some final thoughts on procedures, methods, food acquisition, and best practices

Developing a scientifically sound set of methods for a dietary intervention that could result in replicable, causally valid results took investigators five years of intensive effort. That was a necessary first step because no such standards, protocols, methods or best practices existed. That absence required investigators to develop those standards and protocols de novo in […]

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Significant changes necessary in order for dietary intervention studies to be causal and replicable

Dietary intervention studies as a whole are inherently flawed and do not produce causal or clinically relevant health recommendations or decisions. Accuracy and replicability of any study depend upon using precise methods under identical conditions using identical materials, reagents, apparatus, and test subjects. Unfortunately, human dietary intervention studies in the scientific literature are fatally confounded […]

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Dosing of a single compound to establish causality in dietary interventions & enable clinically valid health decisions.

“Inconsistent and contradictory results from nutrition studies conducted by different investigators continue to emerge, in part because of the inherent variability of natural products, as well as the unknown and therefore uncontrolled variables in study populations and experimental designs.” — The Challenge of Reproducibility and Accuracy in Nutrition Research: Resources and Pitfalls Dietary studies are […]

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Micro- and Nanoplastics: Health Implications

Microplastics are generally those fragments that are less than five millimeters in size. However, a single microplastic fragment rarely stays the same size.   Whether found on dry land, in steams, and oceans — or in your mouth as you chew, swallow, and digest — natural and biological forces relentlessly reduce microplastics in size. Eventually, […]

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